ORM1 anticorps (HRP)

N° du produit ABIN7565737

Cet anticorps Lapin Polyclonal détecte spécifiquement ORM1 dans WB, IHC, ELISA et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour ORM1 anticorps (HRP) (ABIN7565737)

Antigène: ORM1 (Orosomucoid 1 (ORM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORM1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Dot Blot (DB)

Détail du produit anti-ORM1 anticorps (HRP)

Fonction: Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugated

Réactivité croisée (Details): Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified a-1-Acid Glycoprotein [Human Plasma].

Attributs du produit: Synonyms: rabbit anti-Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugation, HRP conjugated rabbit anti-Alpha-1-Acid Glycoprotein 1 Antibody, AGP1, AGP 1, OMD 1, OMD1, Orosomucoid-1

Purification: Anti-Alpha-1-Acid Glycoprotein Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

Stérilité: Sterile filtered

Immunogène:

Immunogen: a-1-Acid Glycoprotein [Human Plasma]

Immunogen Type: Native Protein

Information d'application

Indications d'application: Application Note: Anti-Alpha-1-Acid Glycoprotein peroxidase Antibody has been tested by ELISA and dot blot and is suitable for Western Blot and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Immunohistochemistry Dilution: 1:500 - 1:2,500 Western Blot Dilution: 1:1,000 - 1:5,000 ELISA Dilution: 1:15,000 Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Preservative: 0.01 % (w/v) Gentamicin Sulfate. Do NOT add Sodium Azide!

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Date de péremption: 12 months

Détails sur ORM1

Antigène: ORM1 (Orosomucoid 1 (ORM1))

Autre désignation: ORM1

Sujet: Background: Alpha-1-Acid Glycoprotein Antibody detects alpha-1-acid glycoprotein (AGP or AAG. ) Alpha-1-acid glycoprotein is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3 % plasma protein).[1] Plasma levels are affected by pregnancy, certain drugs, and certain diseases, particularly HIV. The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic drugs (whereas albumin carries acidic drugs), steroids, and protease inhibitors. Aging causes a small decrease in plasma albumin levels, if anything, there is a small increase in α1 acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal. Anti-Alpha-1-Acid Glycoprotein Antibody is ideal for investigators involved in infectious disease and cell cycle protein research.

ID gène: 5004

NCBI Accession: NP_000598

UniProt: P02763

Pathways: Response to Growth Hormone Stimulus